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Eric P. Winer, M.D.
Breast Cancer


Dr. Eric P. Winer is a leading expert in breast carcinoma and is Director of the Breast Oncology Center at the Dana-Farber Cancer Institute. Dr. Winer is also the Associate Professor of Medicine at Harvard Medical School, and a member of the Executive Committee of Cancer and Leukemia Group B (CALGB).

Dr. Winer is a recipient of numerous awards for teaching and clinical research to include the American Cancer Society Career Development Award, Wendell Rosse Award for Excellence in Teaching, R. Wayne Rundles Award for Excellence in Cancer Research, and Joseph Sokal Memorial Lectureship. Dr. Winer received his medical degree at Harvard Medical School in Boston, Massachusetts. He did his residency in Medicine at Beth Israel Hospital in Boston, Massachusetts and at Stanford University in Stanford, California. Dr. Weiner was a Fellow in Oncology, at the Division of Oncology at Stanford University Medical Center in Stanford, California.

 

 
 

Scientific Publications:

Bluman LG, Rimer BK, Sterba KR, Lancaster J, Clark S, Borstelmann N, Iglehart JD, Winer EP: Attitudes, knowledge, risk perceptions and decision-making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses. In press, Psycho-Oncology.

Burstein HJ, Harris LN, Gelman R, Lester SC, Nunes RA, Kaelin CM, Parker LM, Ellisen LW, Kuter I, Gadd MA, Christian RL, Kennedy PR, Borges VF, Bunnell CA, Younger J, Smith BL, Winer EP: Preoperative therapy with Trastuzumab and Paclitaxel followed by sequential adjuvant Doxorubicin/Clyclophosphamide for HER2 overexpressing stage II or III breast cancer. In press, J Clin Oncol.

Burstein HJ, Harris LN, Gelman R, Lester SC, Nunes RA, Kaelin CM, Parker LM, Ellisen LW, Kuter I, Gadd MA, Christian RL, Kennedy PR, Borges VF, Bunnell CA, Younger J, Smith BL, Winer EP: Preoperative therapy with Trastuzumab and Paclitaxel followed by sequential adjuvant Doxorubicin/Clyclophosphamide for HER2 overexpressing stage II or III breast cancer. In press, J Clin Oncol.

Campos S, Winer E: Hormonal therapy in postmenopausal women with breast cancer. In press, Oncology.

Harris LN, Batist G, Belt R, Rovira D, Navari R, Azarnia N, Wells L, Winer, EP. Liposome-encapsulated Doxorubicin compared to conventional Doxorubicin in a randomized multicenter trial as first-line therapy of metastatic breast cancer. Cancer 2002;94:25-36.

Partridge AH, Avorn J, Wang PS, Winer EP: Adherence to therapy with oral anineoplastic agents. J Natl Cancer Inst 2002;94(9):652-661.

Schuchter LM, Hensley ML, Meropol NJ, Winer EP: 2002 Update of recommendation for the use of chemotherapy and radiotherapy protectants: Clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2002;20(12):2895-2903.

Ligibel JA, Winer EP: Trastuzumab/Chemotherapy combinations in metastatic breast cancer. Semin Oncol 2002;29(3), Suppl 11:38-43.

Partridge AH, Winer EP: Informing clinical trial participants about study results. JAMA. 2002;288(3):363-365.

Winer EP, Hudis C, Burstein HJ, Chlebowski RT, Ingle JN, Edge SB, Mamounas EP, Gralow J, Goldstein LJ, Pritchard KI, Braun S, Cobleigh MA, Langer AS, Perotti J, Powles TJ, Whelan TJ, Browman GP: American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for women with hormone receptor-positive breast cancer: status report 200. J Clin Oncol 2002 Aug 1;20(15):3317-3327.

Chlebowski RT, Col N, Winer EP, Collyar DE, Cummings SR, Vogel VG 3rd, Burstein HJ, Eisen A, Lipkus I, Pfister DG: American Society of Clinical Oncology technology assessment of pharmacologic interventions for breast cancer risk reduction including tamoxifen, raloxifene, and aromatase inhibition. J Clin Oncol 2002 Aug 1;20(15):3328-43.

Skinner, CS, Schildkraut J, Berry D, Marcom PK, Sugarman J, Winer EP: Pre-counseling education materials for BRCA testing: Does tailoring make a difference? Genetic Testing 2002 6(2):93-105.

Demark-Wahnefried W, Peterson B, Winer EP, Marks LM, Aziz N, Marcom PK, Blackwell K, Rimer B: Changes in weight, body composition, and factors influencing energy balance among premenopausal breast cancer patients receiving adjuvant chemotherapy. J Clin Oncol. 2001;19(9):2381-2389.

Burstein HJ, Kuter I, Campos SM, Gelman RS, Tribou L, Parker LM, Manola J, Younger J, Matulonis U, Bunnell CA, Partridge AH, Richardson PG, Clarke K, Shulman LN, Winer EP: Clinical activity of trastuzumab and vinorelbine in women with HER2 overexpressing metastatic breast cancer. J Clin Oncol. 2001;19(10):2722-27-30.

Gabrilove JL, Cleeland CS, Livingston RB, Sarokhan B, Winer E, Einhorn LH. Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: improvements in hemoglobin and quality of life similar to three-times-weekly dosing. J Clin Oncol. 2001;19(11):2875-2882.

Burstein HJ, Bunnell CA, Winer EP: New cytotoxic agents and schedules for advanced breast cancer. Sem Onc 2001;28(4):344-358.

Sparano JA, Winer EP: Liposomal anthracyclines for breast cancer. Semin Oncol 2001;Aug;28(4 Suppl 12):32-40.

Bluman L, Borstelmann NA, Iglehart JD, Rimer B, Winer EP: Knowledge, satisfaction, and perceived cancer risk among women diagnosed with DCIS. J Women's Health 2001;10(6):589-598.

Winer EP, Burstein HJ. New combinations with Herceptin® in metastatic breast cancer. Oncology 2001;Oct;61 Suppl S2:50-57.

Partridge AH, Bunnell CA, Winer EP: Quality of life issues among women undergoing high-dose chemotherapy for breast cancer. Breast Disease 2001;14:41-50.

Partridge AH, Burstein HJ, Winer EP. Side effects of chemotherapy and combined chemohormonal therapy in women with early stage breast cancer. J Natl Cancer Inst Monogr 2001;30:135-142.

Dawson NA, Conaway M, Halabi S, Winer EP, Small EJ, Lake D, Vogelzang NJ: A randomized study comparing standard versus moderately high dose megestrol acetate for patients with advanced prostate carcinoma: Cancer and Leukemia Group B (CALBG) Study 9181. Cancer 2000;88:825-834.

Burstein HJ, Manola J, Younger J, Parker LM, Bunnell CA, Scheib R, Matulonis UA, Garber JE, Clarke KD, Shulman LN, Winer EP: Docetaxel administered on a weekly basis for metastatic breast cancer. J Clin Oncol 2000;18:1212-1219.

Miron A, Schildkraut JM, Rimer BK, Winer EP, Skinner CS, Futreal PA, Culler D, Calingaert B, Clark S, Kelly Marcom P, Iglehart JD: Testing for hereditary breast cancer and ovarian cancer in the southestern United States. Ann Surg 2000;231:624-634.

Clark S, Bluman LG, Borstelmann N, Regan K, Winer EP, Rimer, BK, Skinner CS: Patient motivation, satisfaction, and coping in genetic counseling and testing for BRCA1 and BRCA2. J Genetic Counseling 2000;9:219-235.

Speice J, Harkness H, Laneri H, Frankel R, Roter D, Kornblith AB, Ahles T, Winer E, Fleishman S, Luber P, Zevon M, McQuellon R, Trief P, Finkel J, Spira J, Greenberg D, Rowland J, Holland JC: Involving family members in cancer care: Focus group considerations of patients and oncological providers. Psycho-Oncology 2000;9(2):101-112.

Baidas SM, Winer EP, Fleming GF, Harris L, Pluda JM, Crawford JG, Yamauchi H, Isaacs Cl, Hanfelt J, Tefft M, Flockhart D, Johnson MD, Hawkins MJ, Lippman ME, Hayes DF: Phase II evaluation of thalidomide in patients with metastatic breast cancer. J Clin Oncol 2000;18:2710-2717.

Burstein HJ, Winer EP. Primary care for breast cancer survivors. N Engl J Med 2000;343:1086-1094.

Carlson RW, Anderson BO, Bensinger W, Cox C, Davidson NE, Edge SB, Farrar WB, Goldstein LJ, Gradishar WJ, Lichter AS, McCormick B, Nabell LM, Reed EC, Silver SM, Smith ML, Somlo G, Theriault RL, Ward JH, Winer EP, Wolff A: : NCCN Practice Guidelines for Breast Cancer. Oncology (Huntingt). 2000(Nov);14(11A):33-49.

Goss PE, Winer EP, Tannock IF, Schwartz LH: Randomized Phase III trial comparing the new potent and selective third-generation aromatase inhibitor vorozole with megestrol acetate in postmenopausal advanced breast cancer patients. J Clin Onc 1999;17:52-63.

Havlin KA, Ramirez MJ, Legler CM, Harris LN, Matulonis UA, Hohneker JA, Hayes DF, Winer EP: Inability to escalate vinorelbine dose intensity using a daily x 3 schedule with and without filgrastim in patients with metastatic breast cancer. Cancer Chemother Pharmacol 1999;43:68-72.

Clark S, Bluman LG, Borstelmann N, Regan K, Winer EP, Rimer BK, Skinner CS: Patients surviving at least twelve months following high dose chemotherapy with autologous bone marrow support. Psycho-Oncology 1999;8:167-176.

Bluman LG, Rimer BK, Berry DA, Borstelmann N, Iglehart JD, Regan K, Schildkraut J, Winer EP: Attitudes, knowledge and risk perceptions of women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2. J Clin Onc 1999;17:1040-1046.

Costanza ME, Weiss RB, Henderson IC, Norton L, Berry DA, Cirrincione C, Winer E, Wood WC, Frei E, McIntyre OR, Schilsky RL: Safety and efficacy of using a single agent or a Phase II agent before instituting standard combination chemotherapy in previously untreated metastatic breast cancer patients: Reports of a randomized study - CALGB 8642. J Clin Onc 1999;17:1397-1406.

Parmigiani G, Berry DA, Winer EP, Tebaldi C, Iglehart JD, Prosnitz LR: Is axillary lymph node dissection indicated for early-stage breast cancer? A decision analysis. J Clin Onc 1999;17:1465-1473.

Carlson RW, Anderson BO, Bensinger W, Cox C, Davidson NE, Edge SB, Farrar WB, Goldstein LJ, Gradishar WJ, Lichter AS, McCormick B, Nabell LM, Reed EC, Silver SM, Smith ML, Somlo G, Theriault RL, Winer EP: Update: NCCN practice guidelines for the treatment of breast cancer. Oncology 1999;13(5A):41-66.

Hensley ML, Schuchter LM, Lindley C, Meropol NJ, Cohen GI, Broder G, Gradishar WJ, Green DM, Langdon RJ, Mitchell RB, Negrin R, Szatrowski TP, Thigpen JT, Von Hoff D, Wasserman TH, Winer EP, Pfister DG: American Society of Clinical Oncology Clinical Practice Guidelines for the Use of Chemotherapy and Radiotherapy Protectants. J Clin Onc 1999;17:3333-3355.

Vogel C, O'Rourke M, Winer E, Hochster H, Chang A, Adamkiewicz B, White R, McGuirt C: Vinorelbine as first-line chemotherapy for advanced breast cancer in women 60 years of age or older. Ann Onc 1999;10:397-402.

Burstein HJ, Ramirez MJ, Petros WP, Clarke KD, Warmuth MA, Marcom PK, Matulonis UA, Parker LM, Harris LN, Winer EP: Phase I study of Doxil and vinorelbine in metastatic breast cancer. Ann Onc. 1999;10:1113-1116.

Kantoff PW, Halabi S, Conaway M, Picus J, Kirschner J, Hars V, Trump D, Winer EP, Vogelzang NJ. Hydrocortisone with or without mitoxantrone in men with hormone-refractory prostate cancer: results of the cancer and leukemia group B 9182 study. J Clin Oncol 1999;17:2506-2513.

Winer E, Lindley C, Hardee M, Sawyer W, Brunatti C, Borstelmann N, Peters W: Quality of life in patients surviving at least twelve months following high dose chemotherapy with autologous bone marrow support. Psycho-Oncology 1999;8:167-176.

Lindley C, Vasa S, Sawyer W, Winer E: Quality of life and preferences for treatment following systemic adjuvant therapy for early stage breast cancer. J Clin Onc 1998;16:1380-1387.

Rimer BK, Sugarman J, Winer E, Bluman LG, Lerman C: Informed consent for BRCA1 and BRCA2 testing. Breast Disease 1998;10(1,2):99-114.

Thompson TE, McCune JS, Bernard SA, Winer EP, Tremont S, Lindley CM: Cancer pain survey: Patient-centered issues in control. J Pain Symptom Manage 1998;15:275-284.

Warmuth MA, Bowen G, Prosnitz LR, Chu L, Broadwater G, Peterson B, Leight G, Winer EP: Complications of axillary lymph node dissection for carcinoma of the breast: A report based on a patient survey. Cancer 1998;83:1362-1368.

Frank TS, Manley SA, Olufunmilayo IO, Cummings S, Garber JE, Bernhardt B, Antman K, Russo D, Wood ME, Mullineau L, Isaacs C, Peshkin B, Buys S, Venne V, Rowley PT, Loader S, Offit K, Robson M, Hampel H, Brener D, Winer EP, Clark S, Weber B, Strong LC, Rieger P, McClure M, Ward BE, Shattuck-Eidens D, Oliphant A, Skolnick MH, Thomas A: Sequence analysis of BRCA1 and BRCA2: Correlation of mutations with family history and ovarian cancer risk. J Clin Onc 1998;16:2417-2425.

Iglehart JD, Miron A, Rimer BK, Winer EP, Berry D, Schildkraut JM: Overestimation of hereditary breast cancer risk. Ann Surg 1998;228(3):375-384.

Bunnell CA and Winer EP: Oral 5-FU analogues in the treatment of breast cancer. Onc 1998;12(10) (supplement):39-43.

Tengs TO, Winer EP, Paddock S, Aguilar-Chavez O, Berry DA,: Testing for the BRCA1 and BRCA2 breast-ovarian cancer susceptibility genes: A decision analysis. Medical Decision Making 1998;18:365-375.

Berry DA, Parmigiani G, Sanchez J, Schildkraut J, Winer E: Probability of carrying a mutation of breast-ovarian cancer gene BRCA1 based on family history. J Natl Cancer Inst 1997;89:227-238.

Demark-Wahnefried W, Rimer BK, Winer EP: Weight gain in women diagnosed with breast cancer. J Am Diet Assoc 1997;97:519-526, 529.

Demark-Wahnefried W, Hars V, Conaway M, Havlin K, Rimer B, McElveen G, Winer E: Reduced rates of metabolism and decreased physical activity in breast cancer patients receiving adjuvant chemotherapy. Am J Clin Nut 1997;65:1495-1501.

Warmuth MA, Sutton LM, Winer EP: A review of hereditary breast cancer: From screening to risk factor modification. Am J Med 1997;102:407-415.

Sutton LM, Warmuth MA, Petros WP, Winer EP: Pharmacokinetics and clinical impact of all-trans retinoic acid in metastatic breast cancer: A phase II trial. Cancer Chemother Pharmacol 1997;40:335-341.

Tessaro I, Borstelmann N, Regan K, Rimer B, Winer E: Genetic testing for susceptibility to breast cancer: Findings from women's focus groups. J Women's Health 1997;6:317-327.

Winer, EP: Treatment options for patients with refractory breast cancer. Onc 1996;10(6) (supplement):16-20.

Fee-Fulkerson K, Conaway MR, Winer EP, Fulkerson CC, Rimer BK, Georgiade G: Factors contributing to patient satisfaction with breast construction using silicone gel implants. Plast Reconst Surg 1996;97:1420-1426.

Chu L, Sutton LM, Peterson BL, Havlin KA, Winer EP: Continuous infusion 5-fluorouracil as first-line therapy for metastatic breast cancer. J Inf Chemo 1996;6:211-216.

Winer EP, Chu L, Spicer DV: Oral vinorelbine (Navelbine) in the treatment of advanced breast cancer. Semin Oncol 1995;22(5) (supplement):72-79.

Jones S, Winer E, Vogel C, Laufman L, Hutchins L, O'Rourke M, Lembersky B, Budman D, Bigley J, Hohneker J: Randomized comparison of vinorelbine and melphalan in anthracycline-refractory advanced breast cancer. 1995;J Clin Onc 13:2567-2574.

Winer EP, Sutton LM: Quality of life after bone marrow transplantation. 1994;Onc 8:19-27.

Winer EP: Quality-of-life research in patients with breast cancer. Cancer 1994;74(1) (supplement):410-415.

Rowinsky EK, Noe DA, Trump DL, Winer EP, Lucas VS, Wargin WA, Hohneker JA, Lubejko B, Sartorius SE, Ettinger DS, Donehower RC: Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors. 1994;J Clin Onc 12:1754-1763.

Demark-Wahnefried W, Winer EP, Rimer BK: Weight gain in women receiving adjuvant chemotherapy for breast cancer. Onc 1994;12:10.

Demark-Wahnefried W, Winer EP, Rimer BK: Why do women gain weight with adjuvant chemotherapy for breast cancer. J Clin Onc 1993;11:1418-1429.

Peters WP, Ross M, Vredenburgh J, Meisenberg B, Marks LB, Winer E, Kurtzberg J, Bast RC, Jones R, Shpall E, Wu K, Rosner G, Gilbert C, Mathias B, Coniglio D, Petros W, Henderson IC, Norton L, Weiss RB, Budman D, Hurd D: High dose chemotherapy and autologous bone marrow support as consolidation after standard dose adjuvant therapy for high-risk primary breast cancer. 1993;J Clin Onc 11:1132-1143.

Winer EP, Fee-Fulkerson K, Fulkerson CC, Georgiade G, Catoe KE, Brunatti C, Conaway M, Holmes V, Rimer BK: Silicone controversy: A survey of women with breast cancer and silicone implants. J Natl Cancer Inst 1993;85:1407-1411.

Panella TJ, Smith DC, Schold SC, Rogers MP, Winer EP, Fine RJ, Crawford J, Herndon JE, Trump DL: Modulation of O6 alkylguanine-DNA alkyltransferase-mediated carmustine resistance using streptozotocin: A Phase I trial. Can Res 1992;52:2456-2459.

Trump DL, Smith DC, Ellis PG, Rogers MP, Schold SC, Winer EP, Panella TJ, Jordan VC, Fine RL: High dose oral tamoxifen, a potential multidrug resistance reversal agent: A Phase I trial in combination with vinblastine. J Natl Cancer Inst 1992;23:1811-1816.

Brizel DM, Winer EP, Prosnitz LR, Scott J, Crawford J, Moore JO, Gockerman JP: Improved survival in advanced Hodgkin's disease with the use of combined modality therapy. Int J Radiat Oncol Biol Phys 1990;19:535-542.

Rosenberg A, Winer EP, Cadman E: The use of adjuvant chemotherapy for breast cancer in a community practice. Conn Med 1985;49:281-285.

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